![]() Sony will release the first season of Silver Spoons, though that's not really "classic" television (are the '80s considered "classic" now? Maybe "semi-classic"?).My "Pick of the Week" goes to Picket Fences, the 1992 series from David E. Warner also has the first season of The Powerpuff Girls, and Shout! Factory will put out the complete Batfink set, featuring 100 episodes (well, they're shorts) on four discs.Fans of classic shows can pick up Voyage to the Bottom of the Sea Season 3, volume 1, Perry Mason Season 2, volume 1, or Daniel Boone Season 4 from Liberation Entertainment. Both shows hit "volume 3" on the same day, though this is the last time they'll be paired together it's the final volume for Pinky. is releasing sets for The Animaniacs and Pinky and the Brain on the 19th. Read more about how to correctly acknowledge RSC content.Animation fans will have a blast on June 19! Warner Bros. Permission is not required) please go to the Copyright If you want to reproduce the wholeĪrticle in a third-party commercial publication (excluding your thesis/dissertation for which If you are the author of this article, you do not need to request permission to reproduce figuresĪnd diagrams provided correct acknowledgement is given. ![]() Provided correct acknowledgement is given. If you are an author contributing to an RSC publication, you do not need to request permission Please go to the Copyright Clearance Center request page. To request permission to reproduce material from this article in a commercial publication, ![]() Provided that the correct acknowledgement is given and it is not used for commercial purposes. This article in other publications, without requesting further permission from the RSC, Pfeifer,Ĭreative Commons Attribution-NonCommercial 3.0 Unported Licence. The proposed device is amenable to the detection of other biomarker panels and thus could open new medical diagnostic avenues for sensitive multi-analyte measurements with low-volume biological sample requirements.Ī novel point-of-care diagnostic prototype system for the simultaneous electrochemiluminescent sensing of multiple traumatic brain injury biomarkers To demonstrate the system's feasibility, current performance and efficiency, the simultaneous detection of three mTBI biomarkers (GFAP, h-FABP, S100β) in 50% serum was achieved in the upper pg mL −1 range. Based on this design concept, further miniaturization, system integration, performance optimization and clinical evaluation shall pave the way towards the development of a portable instrument for use at the site of accident and healthcare. The small tabletop prototype consists of a screen-printed electrode compartment to conduct multi-analyte ECL sandwich assays, a potentiostat module and a light collection module, all integrated into a compact 3D-printed housing (18.2 × 16.5 × 5.0 cm), as well as an sCMOS detector. Herein, we report a novel prototype system designed as a precursor of a future hand-held point-of-care (POC) diagnostic device for the simultaneous multi-biomarker sensing, employing a microarray-type spatially resolved electrochemiluminescence immunoassay (SR-ECLIA). Recent studies suggest that a screening test based on the measurement of a protein biomarker panel directly from a patient's blood can facilitate mTBI diagnosis. A high percentage (70–85%) of all TBI patients are suffering from mild TBI (mTBI), which is often difficult to detect and diagnose with standard imaging tools (MRI, CT scan) due to the absence of significant lesions and specific symptoms. Traumatic brain injuries (TBI) are typically acquired when a sudden violent event causes damage to the brain tissue.
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